Longitudinal analysis of cognitive decline in amnestic MCI subjects using
multiple imputation
 
   Lead Investigator:    Danping Liu
   Institution      :    NIH
   E-Mail           :    danping.liu@nih.gov
   Proposal ID      :    341



   Proposal Description:
   The aim of this study is to demonstrate the use of multiple imputation with chained equation (MICE) in analyzing longitudinal data in observational cohort studies. This analysis will appear as an example in Chapter 5 of Applied Missing Data Analysis in Health Sciences (Authors: Xiao-Hua Zhou, Chuan Zhou, Danping Liu and Xiaobo Ding). We are planning to reanalyze the same data set used in Monsell et al. (2012) (Comparing measures of decline to dementia in amnestic MCI subjects in the National Alzheimer???s Coordinating Center (NACC) Uniform Data Set, International Psychogeriatrics, 24, 1553-1560).  No response to update request